SCHEMBL28877972

SCHEMBL28877972

Cc1ccc(-c2cc(Br)ccc2S(N)(=O)=O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.47
PTGS1 P23219 2/20 0.47
CA12 O43570 5/20 0.42
CA2 P00918 5/20 0.42
CA9 Q16790 5/20 0.42
CA1 P00915 4/20 0.41
CA3 P07451 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
PTGES2 Q9H7Z7 2/20 0.40
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
SLC9A1 P19634 1/20 0.38
MAOA P21397 1/20 0.38
LOX P28300 1/20 0.38
KCNH2 Q12809 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
F10 P00742 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4734280 0.86 PTGS2 (0.53) PTGS2PTGS1CA12CA2CA9
SCHEMBL28134928 0.83 PTGS2 (0.44) PTGS2PTGS1CA2CA9CA1
SCHEMBL21590167 0.76 HDAC3 (0.47) PTGS2CA12CA2CA9CA1
SCHEMBL1045784 0.76 ALDH1A1 (0.50) PTGS2PTGS1ALDH1A1KDM4EMAOA
SCHEMBL8597605 0.76 HDAC7 (0.45) PTGS2PTGS1CA12CA2CA9
SCHEMBL29588197 0.76 HDAC7 (0.45) PTGS2PTGS1CA12CA2CA9
SCHEMBL31453311 0.76 ALDH1A1 (0.41) PTGS2PTGS1CA12CA2CA9
SCHEMBL28327116 0.75 CA2 (0.46) CA12CA2CA9CA1CA6
Hydrochloric Acid SCHEMBL5795789 0.75 PTGS2 (0.50) PTGS2PTGS1MAOALOXL2
SCHEMBL8552729 0.75 CA2 (0.53) PTGS2PTGS1CA12CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106496373-B Catalytic component and its preparation and application for olefinic polymerization 中国石油化工股份有限公司 2019-09-27 CN disclosed