Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16780594 | 1.00 | HDAC4 (0.46) | HDAC4ADORA2AADORA1DHODHALDH1A1 | |
| SCHEMBL28104975 | 0.85 | ALDH1A1 (0.42) | HDAC4DHODHALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL13458062 | 0.80 | GABRA1 (0.52) | HDAC4DHODHALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL121970 | 0.79 | RAB9A (0.50) | HDAC4ADORA2ADHODHMAPK1SMN1; SMN2 | |
| SCHEMBL29959678 | 0.79 | RAB9A (0.50) | HDAC4ADORA2ADHODHMAPK1SMN1; SMN2 | |
| SCHEMBL8467926 | 0.78 | HDAC4 (0.46) | HDAC4DHODHALDH1A1METAP2SMN1; SMN2 | |
| SCHEMBL3458918 | 0.78 | NPY5R (0.47) | HDAC4DHODHALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL218007 | 0.78 | L3MBTL1 (0.49) | HDAC4DHODHALDH1A1METAP2SMN1; SMN2 | |
| SCHEMBL8138043 | 0.78 | MAPT (0.56) | HDAC4DHODHALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL6850684 | 0.78 | SLC6A2 (0.49) | HDAC4DHODHALDH1A1MAPK1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513020-B | KDM1A inhibitors for the treatment of diseases | 伊美格生物科学公司 | 2024-02-23 | — | — | CN | disclosed |