SCHEMBL28878385

SCHEMBL28878385

Cc1ccccc1[Se]C=C(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MCOLN3 Q8TDD5 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
HPGD P15428 2/20 0.35
POLB P06746 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
TP53 P04637 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
NFKB1 P19838 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28329617 0.77 CES2 (0.35) ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1
SCHEMBL28328450 0.76 NPSR1 (0.38) ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1
SCHEMBL28328374 0.74 CYP1A2 (0.38) ALDH1A1CYP1A2CYP2C9CYP2C19HPGD
SCHEMBL28328449 0.73 CES2 (0.44) ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1
SCHEMBL28329612 0.73 KCNK3 (0.39) ALDH1A1HPGDMAOAMAOBSMN1; SMN2
SCHEMBL28329637 0.73 BBOX1 (0.40) ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1
SCHEMBL28328372 0.72 CES2 (0.47) ALDH1A1NPSR1CES2CES1HPGD
SCHEMBL28329615 0.69 SMN1; SMN2 (0.45) ALDH1A1POLBMAPTSMN1; SMN2ACHE
SCHEMBL9806295 0.65 ALDH1A1 (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1
SCHEMBL6548199 0.65 NPC1 (0.42) ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110452145-B Synthetic method of alpha, beta-unsaturated selenium compound 温州大学 2021-04-13 CN disclosed
CN-110452145-A α, β-unsaturation selenium class compound synthetic method UNIV WENZHOU 2019-11-15 CN disclosed