SCHEMBL28328374

SCHEMBL28328374

C([Se]c1cccc2ccccc12)=C(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.38
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
ACP3 P15309 1/20 0.36
NR4A1 P22736 1/20 0.36
NR4A2 P43354 1/20 0.36
NR4A3 Q92570 1/20 0.36
CTNNB1 P35222 1/20 0.35
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
GAA P10253 1/20 0.35
EPHX1 P07099 1/20 0.34
MRGPRX4 Q96LA9 1/20 0.34
ALDH1A1 P00352 3/20 0.33
HSD17B10 Q99714 3/20 0.33
TDP1 Q9NUW8 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28329617 0.74 CES2 (0.35) CYP1A2CYP2C9CYP2C19KMT2AMEN1
SCHEMBL28878385 0.74 ALDH1A1 (0.36) CYP1A2CYP2C9CYP2C19GAAALDH1A1
SCHEMBL28328424 0.70 ALOX5 (0.39)
SCHEMBL28329637 0.70 BBOX1 (0.40) CYP1A2CYP2C9CYP2C19ALDH1A1TDP1
SCHEMBL7695549 0.68 KDM4E (0.47) CYP1A2NPC1RAB9ACYP3A4CYP2D6
SCHEMBL31243217 0.67 ALDH1A1 (0.50) CYP1A2CYP3A4CYP2C9CYP2C19NR4A1
SCHEMBL1059102 0.67 ALDH1A1 (0.50) CYP1A2CYP3A4CYP2C9CYP2C19NR4A1
SCHEMBL28140673 0.67 ALDH1A1 (0.50) CYP1A2CYP3A4CYP2C9CYP2C19NR4A1
SCHEMBL9806349 0.67 NR4A1 (0.52) CYP1A2NPC1RAB9ACYP3A4CYP2D6
SCHEMBL9806354 0.67 NR4A1 (0.52) CYP1A2NPC1RAB9ACYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110452145-B Synthetic method of alpha, beta-unsaturated selenium compound 温州大学 2021-04-13 CN disclosed
CN-110452145-A α, β-unsaturation selenium class compound synthetic method UNIV WENZHOU 2019-11-15 CN disclosed