SCHEMBL28879261

SCHEMBL28879261

Cc1cccc(N(C)c2ccc3c(c2N(C)c2cccc(C)c2C)C(=O)c2ccccc2C3=O)c1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.51
ALDH1A1 P00352 7/20 0.51
L3MBTL1 Q9Y468 7/20 0.51
MAPK1 P28482 6/20 0.51
EGFR P00533 4/20 0.51
TDP1 Q9NUW8 4/20 0.51
LMNA P02545 3/20 0.51
NSD2 O96028 2/20 0.51
SMN1; SMN2 Q16637 6/20 0.43
RAB9A P51151 5/20 0.43
NPC1 O15118 3/20 0.43
CYP3A4 P08684 2/20 0.43
TSHR P16473 2/20 0.43
CASP3 P42574 1/20 0.43
HBB P68871 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
ELANE P08246 1/20 0.43
PABPC1 P11940 4/20 0.43
KDM4E B2RXH2 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11605652 0.90 ALDH1A1 (0.51) MAPTALDH1A1L3MBTL1MAPK1EGFR
SCHEMBL7601575 0.87 ALDH1A1 (0.63) MAPTALDH1A1L3MBTL1MAPK1EGFR
SCHEMBL11537181 0.78 ADORA2A (0.51) MAPTALDH1A1L3MBTL1MAPK1EGFR
SCHEMBL9844713 0.76 ALDH1A1 (0.79) MAPTALDH1A1L3MBTL1MAPK1EGFR
SCHEMBL11800770 0.75 ALDH1A1 (0.51) MAPTALDH1A1L3MBTL1MAPK1EGFR
SCHEMBL5436537 0.72 TRPA1 (0.44) MAPTALDH1A1MAPK1LMNASMN1; SMN2
SCHEMBL18984780 0.71 ALDH1A1 (0.66) MAPTALDH1A1L3MBTL1MAPK1EGFR
SCHEMBL10885242 0.71 ALDH1A1 (0.53) MAPTALDH1A1L3MBTL1MAPK1EGFR
SCHEMBL29501107 0.70 ALDH1A1 (0.67) MAPTALDH1A1L3MBTL1MAPK1EGFR
SCHEMBL57336 0.70 ALDH1A1 (0.67) MAPTALDH1A1L3MBTL1MAPK1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110520460-A Process for the preparation of poly (alkylene furandicarboxylate) DU PONT 2019-11-29 CN disclosed
CN-110520459-A Process for preparing poly (trimethylene furandicarboxylate) using zinc catalyst DUPONT IND BIOSCIENCES USA LLC 2019-11-29 CN disclosed