Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | PRNP | P04156 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558137 | 0.80 | MAPT (0.46) | SLC22A12SMN1; SMN2L3MBTL1KMT2AKDM4E | |
| SCHEMBL30292662 | 0.79 | ALDH1A1 (0.50) | SLC22A12SMN1; SMN2L3MBTL1KMT2AKDM4E | |
| SCHEMBL30292657 | 0.79 | ALDH1A1 (0.50) | SLC22A12SMN1; SMN2L3MBTL1KMT2AKDM4E | |
| SCHEMBL6906435 | 0.79 | ALDH1A1 (0.50) | SLC22A12SMN1; SMN2L3MBTL1KMT2AKDM4E | |
| SCHEMBL15468462 | 0.78 | SLC22A12 (0.57) | SLC22A12HTTSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL2222831 | 0.77 | ALDH1A1 (0.50) | SLC22A12HTTL3MBTL1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL7279409 | 0.76 | ALDH1A1 (0.49) | SLC22A12HTTL3MBTL1KMT2AKDM4E | |
| SCHEMBL2883252 | 0.76 | SMN1; SMN2 (0.62) | SLC22A12SMN1; SMN2KDM4EPOLBGAA | |
| SCHEMBL3728246 | 0.76 | SMN1; SMN2 (0.76) | HTTSMN1; SMN2L3MBTL1KMT2AKDM4E | |
| SCHEMBL30863845 | 0.75 | KDM4C (0.57) | L3MBTL1KMT2AKDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608436-B | Substituted methyl formyl reagents and methods of using same to improve physicochemical and/or pharmacokinetic properties of compounds | 斯法尔制药私人有限公司 | 2022-10-11 | — | — | CN | disclosed |