Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.32 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5638554 | 0.83 | SMN1; SMN2 (0.44) | CTSKMAPTEPHX2SMN1; SMN2TUBB4A | |
| SCHEMBL28879479 | 0.80 | — | — | |
| SCHEMBL8432418 | 0.79 | CTSK (0.35) | CTSKMAPTEPHX2SMN1; SMN2TUBB4A | |
| SCHEMBL11419405 | 0.79 | CHRNB2 (0.46) | MAPTALOX15ALDH1A1KMT2ACHRNB2 | |
| SCHEMBL15759434 | 0.79 | CYP2D6 (0.46) | CTSKMAPTEPHX2SMN1; SMN2RAB9A | |
| SCHEMBL13662175 | 0.78 | MME (0.46) | CTSKMAPTFAAHALDH1A1 | |
| SCHEMBL10874284 | 0.78 | CHRNB2 (0.45) | MAPTEPHX2SMN1; SMN2USP2TSHR | |
| SCHEMBL28285725 | 0.77 | — | — | |
| SCHEMBL7603541 | 0.76 | ANPEP (0.40) | SMN1; SMN2RAB9ABRD4ALOX15ALDH1A1 | |
| SCHEMBL10972245 | 0.76 | ACHE (0.55) | ALOX15ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608436-B | Substituted methyl formyl reagents and methods of using same to improve physicochemical and/or pharmacokinetic properties of compounds | 斯法尔制药私人有限公司 | 2022-10-11 | — | — | CN | disclosed |