SCHEMBL28879496

SCHEMBL28879496

CCCC(c1ccc(OC2CCCCO2)cc1)C(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
DHFR P00374 1/20 0.34
TNK2 Q07912 3/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
HSD11B1 P28845 1/20 0.34
KDM4C Q9H3R0 1/20 0.32
PDE4A P27815 2/20 0.32
PDE4B Q07343 2/20 0.32
PDE4C Q08493 2/20 0.32
PDE4D Q08499 2/20 0.32
GPR88 Q9GZN0 1/20 0.32
SLC6A3 Q01959 2/20 0.31
FFAR1 O14842 1/20 0.31
ACACB O00763 1/20 0.31
NPY1R P25929 1/20 0.31
NPY2R P49146 1/20 0.31
NPY4R P50391 1/20 0.31
NPY5R Q15761 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28879518 0.82 PDE4B (0.34) PDE4APDE4BPDE4CPDE4D
SCHEMBL11769693 0.81 MEN1 (0.36) MEN1KMT2ADHFRTNK2NPC1
SCHEMBL825397 0.80 ALDH1A1 (0.43) MEN1KMT2ADHFRTNK2
SCHEMBL14049220 0.80 ALDH1A1 (0.43) MEN1KMT2ADHFRTNK2
SCHEMBL7003731 0.79 KMT2A (0.38) MEN1KMT2ADHFRTNK2NPC1
SCHEMBL12949447 0.79 MEN1 (0.38) MEN1KMT2ADHFRTNK2NPC1
SCHEMBL7774785 0.79 KMT2A (0.40) MEN1KMT2ADHFRTNK2NPC1
SCHEMBL7231881 0.79 KMT2A (0.40) MEN1KMT2ADHFRTNK2NPC1
SCHEMBL23676925 0.78 DHFR (0.38) MEN1KMT2ADHFRTNK2NPC1
SCHEMBL8028966 0.78 HSD11B1 (0.37) MEN1KMT2ADHFRTNK2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115298227-B Group III and lanthanide bis-phenyl-phenoxy metal-ligand complexes 陶氏环球技术有限责任公司 2024-06-04 CN disclosed
CN-117069749-A Group III and lanthanide bis-phenyl-phenoxy metal-ligand complexes 陶氏环球技术有限责任公司 2023-11-17 CN disclosed
CN-115298227-A Group III and lanthanide bis-phenyl-phenoxy metal-ligand complexes 陶氏环球技术有限责任公司 2022-11-04 CN disclosed