Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260786 | 0.83 | KMT2A (0.64) | KMT2ALMNAHSD17B10L3MBTL1HPGD | |
| SCHEMBL11047626 | 0.79 | KMT2A (0.59) | KMT2ALMNAHSD17B10L3MBTL1HPGD | |
| SCHEMBL195563 | 0.79 | KMT2A (0.59) | KMT2ALMNAHSD17B10L3MBTL1HPGD | |
| SCHEMBL7609753 | 0.79 | LOXL2 (0.59) | KMT2ALMNAHSD17B10HPGDMAPT | |
| SCHEMBL26327985 | 0.78 | KMT2A (0.57) | KMT2ALMNAHSD17B10L3MBTL1HPGD | |
| SCHEMBL4101066 | 0.78 | KMT2A (0.57) | KMT2ALMNAHSD17B10L3MBTL1HPGD | |
| SCHEMBL28879940 | 0.77 | MAOB (0.47) | KMT2ALMNARAB9AMAOBMAOA | |
| SCHEMBL2642382 | 0.76 | KMT2A (0.67) | KMT2ALMNAHSD17B10L3MBTL1HPGD | |
| SCHEMBL6859304 | 0.75 | KMT2A (1.00) | KMT2ALMNAHSD17B10L3MBTL1HPGD | |
| SCHEMBL9818052 | 0.75 | KMT2A (0.73) | KMT2ALMNAHSD17B10L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |