Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27776368 | 0.85 | HTT (0.42) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL28880397 | 0.84 | NPC1 (0.35) | LPAR1ALDH1A1CYP2C9CYP2C19LMNA | |
| SCHEMBL28880435 | 0.81 | ALDH1A1 (0.38) | ALDH1A1MAPTLMNAL3MBTL1RAB9A | |
| SCHEMBL28880510 | 0.79 | HTT (0.39) | LPAR1ALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL28880508 | 0.79 | HTT (0.39) | LPAR1ALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL28602971 | 0.76 | MAPT (0.36) | ALDH1A1MAPTLMNAHPGDL3MBTL1 | |
| SCHEMBL27725340 | 0.74 | GAA (0.41) | ALDH1A1CYP2C9LMNAMEN1KMT2A | |
| SCHEMBL27725207 | 0.74 | GAA (0.41) | ALDH1A1CYP2C9LMNAMEN1KMT2A | |
| SCHEMBL28880330 | 0.74 | HTT (0.41) | CYP2C9CYP2C19CYP1A2CYP3A4MAPT | |
| SCHEMBL29163982 | 0.74 | TAS2R14 (0.39) | LPAR1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |