Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880510 | 1.00 | HTT (0.39) | HTTTSHRAPOBEC3AAPOBEC3GNCOA1 | |
| SCHEMBL11026259 | 0.82 | HTT (0.44) | HTTTSHRCYP2C9CYP2C19CYP1A2 | |
| SCHEMBL28880382 | 0.81 | HTT (0.35) | HTTCYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL28880383 | 0.81 | HTT (0.35) | HTTCYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL28880329 | 0.79 | LPAR1 (0.37) | HTTCYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL28880525 | 0.78 | SOS1 (0.35) | TSHRKMT2APARP1ALDH1A1MAPT | |
| SCHEMBL28880523 | 0.78 | SOS1 (0.35) | TSHRKMT2APARP1ALDH1A1MAPT | |
| SCHEMBL31159323 | 0.78 | TSHR (0.34) | HTTTSHRAPOBEC3AAPOBEC3GNCOA1 | |
| SCHEMBL27823919 | 0.78 | CYP2C9 (0.38) | HTTTSHRAPOBEC3AAPOBEC3GCYP2C9 | |
| SCHEMBL2899680 | 0.76 | PTGS2 (0.46) | TSHRCYP2C9CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |