Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880408 | 1.00 | TRPM8 (0.31) | TRPM8CES2CES1 | |
| SCHEMBL28880414 | 0.78 | TRPA1 (0.32) | — | |
| SCHEMBL28880416 | 0.78 | TRPA1 (0.32) | — | |
| SCHEMBL31159352 | 0.77 | — | — | |
| SCHEMBL28657169 | 0.73 | CA9 (0.39) | CES2CES1 | |
| SCHEMBL28657167 | 0.73 | CA9 (0.39) | CES2CES1 | |
| SCHEMBL28690149 | 0.73 | CES2 (0.40) | TRPM8CES2CES1 | |
| SCHEMBL28690146 | 0.73 | CES2 (0.40) | TRPM8CES2CES1 | |
| SCHEMBL23526123 | 0.72 | PDE2A (0.35) | — | |
| SCHEMBL23526125 | 0.72 | PDE2A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |