Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880414 | 1.00 | TRPA1 (0.32) | TRPA1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL28880354 | 0.87 | SOS1 (0.34) | TRPA1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL28880355 | 0.87 | SOS1 (0.34) | TRPA1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL28880408 | 0.78 | TRPM8 (0.31) | — | |
| SCHEMBL28880406 | 0.78 | TRPM8 (0.31) | — | |
| SCHEMBL23526350 | 0.75 | SOS1 (0.35) | SOS1CYP11B2CYP11B1ALK | |
| SCHEMBL29945727 | 0.75 | SOS1 (0.35) | SOS1CYP11B2CYP11B1ALK | |
| SCHEMBL23526352 | 0.75 | SOS1 (0.35) | SOS1CYP11B2CYP11B1ALK | |
| SCHEMBL9821165 | 0.75 | CYP11B1 (0.39) | SOS1CYP11B2CYP11B1 | |
| SCHEMBL22763993 | 0.74 | SOS1 (0.36) | SOS1CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |