SCHEMBL29616775

SCHEMBL29616775

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nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.40
SLC15A1 P46059 1/20 0.38
TAS2R38 P59533 1/20 0.37
SPHK1 Q9NYA1 2/20 0.36
GLS O94925 1/20 0.35
PAX8 Q06710 1/20 0.34
ESR2 Q92731 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
ESR1 P03372 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
NPY1R P25929 1/20 0.34
PTGS2 P35354 1/20 0.34
OPRD1 P41143 1/20 0.34
MTOR P42345 1/20 0.34
HK2 P52789 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
THPO P40225 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11888829 1.00 CRBN (0.40) CRBNSLC15A1TAS2R38SPHK1GLS
SCHEMBL27814309 0.85 SLC15A1 (0.43) SLC15A1SPHK1GLSPAX8ESR2
SCHEMBL14725064 0.81 SLC15A1 (0.42) CRBNSLC15A1TAS2R38CYP3A4SLC1A1
SCHEMBL8657756 0.80 SLC15A1 (0.40) CRBNSLC15A1TAS2R38PAX8
SCHEMBL11113223 0.79 CRBN (0.39) CRBNSLC15A1TAS2R38ALDH1A1
SCHEMBL11112208 0.79 CRBN (0.39) CRBNSLC15A1TAS2R38ALDH1A1
SCHEMBL388604 0.79 PTGS1 (0.46) CRBNSLC15A1TAS2R38KDM4EPTGS2
SCHEMBL388605 0.79 PTGS1 (0.46) CRBNSLC15A1TAS2R38KDM4EPTGS2
SCHEMBL4411446 0.79 TGFBR1 (0.44) SLC15A1SPHK1GLSPAX8ESR2
SCHEMBL2888048 0.78 ESR2 (0.39) SLC15A1SPHK1GLSPAX8ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022106611-A1 NOVEL COMPOSITIONS OF BETA-LACTAM COMPOUNDS XELLIA PHARMACEUTICALS APS (DK) 2022-05-27 WO claimed
WO-2022106630-A1 STABLE FORMULATIONS COMPRISING PIPERACILLIN AND/OR TAZOBACTAM XELLIA PHARMACEUTICALS APS (DK) 2022-05-27 WO claimed
WO-2022106611-A1 NOVEL COMPOSITIONS OF BETA-LACTAM COMPOUNDS XELLIA PHARMACEUTICALS APS (DK) 2022-05-27 WO disclosed
WO-2022106630-A1 STABLE FORMULATIONS COMPRISING PIPERACILLIN AND/OR TAZOBACTAM XELLIA PHARMACEUTICALS APS (DK) 2022-05-27 WO disclosed