Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.35 |
| ▸ | TUBB | P07437 | 2/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2899680 | 0.88 | PTGS2 (0.46) | CYP2C9CYP2C19MEN1KMT2ATSHR | |
| SCHEMBL32681778 | 0.80 | KMT2A (0.36) | CYP2C9CYP2C19MEN1KMT2AHTT | |
| SCHEMBL3065896 | 0.80 | KMT2A (0.36) | CYP2C9CYP2C19MEN1KMT2AHTT | |
| SCHEMBL29731059 | 0.80 | KMT2A (0.36) | CYP2C9CYP2C19MEN1KMT2AHTT | |
| SCHEMBL1680252 | 0.80 | KMT2A (0.36) | CYP2C9CYP2C19MEN1KMT2AHTT | |
| SCHEMBL618635 | 0.80 | GABRA1 (0.41) | CYP2C9CYP2C19MEN1KMT2ATSHR | |
| SCHEMBL23526320 | 0.78 | HTT (0.46) | CYP2C9CYP2C19MEN1KMT2AHTT | |
| SCHEMBL28880510 | 0.78 | HTT (0.39) | CYP2C9CYP2C19MEN1KMT2AHTT | |
| SCHEMBL30014041 | 0.78 | HTT (0.46) | CYP2C9CYP2C19MEN1KMT2AHTT | |
| SCHEMBL23526323 | 0.78 | HTT (0.46) | CYP2C9CYP2C19MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101981034-B | Triazolopyridazines as PAR1 inhibitors, their preparation and their use for producing medicaments | SANOFI AVENTIS | 2013-08-14 | — | — | CN | disclosed |
| CN-101981034-A | Triazolopyridazines as PAR1 inhibitors, their preparation and their use as medicaments | SANOFI AVENTIS | 2011-02-23 | — | — | CN | disclosed |