Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1285795 | 1.00 | LMNA (0.47) | LMNATHRBOPRM1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL22117628 | 0.97 | LMNA (0.45) | LMNATHRBOPRM1 | |
| SCHEMBL9681077 | 0.78 | LMNA (0.39) | LMNATHRB | |
| SCHEMBL27803885 | 0.78 | THRB (0.44) | LMNATHRB | |
| SCHEMBL5891559 | 0.78 | THRB (0.44) | LMNATHRB | |
| SCHEMBL1568155 | 0.75 | THRB (0.57) | LMNATHRB | |
| SCHEMBL379036 | 0.75 | THRB (0.42) | LMNATHRB | |
| SCHEMBL6676705 | 0.75 | — | — | |
| SCHEMBL7166173 | 0.75 | TSHR (0.41) | LMNATHRBALDH1A1 | |
| SCHEMBL5662268 | 0.75 | TSHR (0.41) | LMNATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153715-B2 | Aminofunctional polyvinylacetals | KURARAY EUROPE GMBH (DE) | 2012-04-10 | — | — | US | claimed |
| US-20090203829-A1 | AMINOFUNCTIONAL POLYVINYLACETALS | WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) | 2009-08-13 | — | — | US | claimed |
| EP-1758943-B1 | Use of aminofunctional polyvinylacetals in printing ink compositions | WACKER POLYMER SYSTEMS GMBH (DE) | 2008-07-16 | — | — | EP | claimed |
| EP-1758943-A1 | AMINOFUNCTIONAL POLYVINYLACETALS | Wacker Polymer Systems GmbH & Co. KG (DE) | 2007-03-07 | — | — | EP | claimed |
| WO-2005118653-A1 | AMINOFUNCTIONAL POLYVINYLACETALS | WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) | 2005-12-15 | — | — | WO | claimed |
| CN-116251226-B | Radiopaque development embolism microsphere and preparation method thereof | 科睿驰（深圳）医疗科技发展有限公司 | 2025-04-08 | — | — | CN | disclosed |
| EP-3792256-B1 | PYRIDINE COMPOUNDS AS PI3K-GAMMA INHIBITORS | INCYTE CORP (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2024093387-A1 | CONTRAST COMPOUND AND METHOD FOR PREPARING SAME, AND IMAGEABLE EMBOLIZATION MATERIAL AND METHOD FOR PREPARING SAME | 科睿驰（深圳）医疗科技发展有限公司 | 2024-05-10 | — | — | WO | disclosed |
| CN-117986193-A | Developing compound and preparation method thereof, developing embolic material and preparation method thereof | 科睿驰（深圳）医疗科技发展有限公司 | 2024-05-07 | — | — | CN | disclosed |
| US-11952367-B2 | Pyridine and pyridimine compounds as PI3K-gamma inhibitors | INCYTE CORPORATION (US) | 2024-04-09 | — | — | US | disclosed |
| CN-116251226-A | Radiopaque development embolism microsphere and preparation method thereof | 科睿驰（深圳）医疗科技发展有限公司 | 2023-06-13 | — | — | CN | disclosed |
| US-20220340544-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION | 2022-10-27 | — | — | US | disclosed |
| EP-0254245-A1 | Hetrazepins and processes for their preparation | BOEHRINGER INGELHEIM KG (DE) | 1988-01-27 | — | — | EP | disclosed |
| EP-0047531-B1 | 2-(1,4-BENZODIOXAN-2-YLALKYL) IMIDAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYNTEX (U.S.A.) INC. (US) | 1985-06-12 | — | — | EP | disclosed |
| US-4497818-A | 2-(1,4-Benzodioxan-2-ylalkyl)imidazoles useful as antihypertensives and platelet aggregation inhibitors | SYNTEX (U.S.A.) INC. (US) | 1985-02-05 | — | — | US | disclosed |
| EP-0047531-A1 | 2-(1,4-Benzodioxan-2-ylalkyl) imidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-03-17 | — | — | EP | disclosed |
| US-4302469-A | 2-(1,4-Benzodioxan-2-ylalkyl)imidazoles useful as antidepressants | SYNTEX (U.S.A.) INC. (US) | 1981-11-24 | — | — | US | disclosed |
| US-4062961-A | SUBSTITUTED 1,2,3,4-TETRAHYDROISOQUINOLINES | SMITHKLINE CORPORATION (US) | 1977-12-13 | — | — | US | disclosed |
| US-3988339-A | 7 OR 8-SUBSTITUTED 1,2,3,4-TETRAHYDRO-ISOQUINOLINE | SMITHKLINE CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |
| US-3939164-A | PHENYLETHANOLAMINE N-METHYL TRANSFERASE INHIBITORS | SMITHKLINE CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220340544-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES AS PI3K INHIBITORS | PIK3CD, PIK3CA, PIK3CG | LMNA 3482/4885THRB 1174/4885OPRM1 4602/4885 |
| US-11952367-B2 | Pyridine and pyridimine compounds as PI3K-gamma inhibitors | PIK3CG, PIK3CD, PIK3CB | LMNA 3680/4885THRB 1368/4885OPRM1 4370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.