SCHEMBL28883140

SCHEMBL28883140

CC(O)CN(CC(C)O)c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.49
LMNA P02545 2/20 0.49
MAPT P10636 9/20 0.49
ALDH1A1 P00352 6/20 0.49
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
RXFP1 Q9HBX9 1/20 0.49
ALOX12 P18054 4/20 0.47
HSD17B10 Q99714 4/20 0.47
ALOX15 P16050 3/20 0.47
TSHR P16473 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
CYP3A4 P08684 2/20 0.47
THRB P10828 1/20 0.47
RECQL P46063 1/20 0.47
ATM Q13315 1/20 0.47
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
NOX1 Q9Y5S8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27220455 0.85 ALDH1A1 (0.46) HPGDLMNAMAPTALDH1A1MEN1
SCHEMBL338524 0.83 POLB (0.44) LMNAALDH1A1HSD17B10TSHRL3MBTL1
SCHEMBL11682436 0.77 ALDH1A1 (0.52) HPGDLMNAMAPTALDH1A1MEN1
SCHEMBL14081010 0.76 KMT2A (0.42) MAPTALDH1A1MEN1KMT2AATM
SCHEMBL29528413 0.76 NR3C1 (0.50) HPGDLMNAMAPTALDH1A1ALOX12
SCHEMBL141889 0.76 NPC1 (0.68) HPGDLMNAMAPTALDH1A1MEN1
SCHEMBL9514595 0.76 NPC1 (0.68) HPGDLMNAMAPTALDH1A1MEN1
SCHEMBL4540287 0.75 RAB9A (0.56) HPGDMAPTALDH1A1MEN1KMT2A
Diphenylamine SCHEMBL11002954 0.74 HSD17B10 (0.67) HPGDLMNAMAPTALDH1A1MEN1
SCHEMBL24090362 0.74 MAPT (0.42) HPGDLMNAMAPTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109153934-B Polyester dispersants, synthesis and uses thereof 雪佛龙奥伦耐有限责任公司 2022-04-05 CN disclosed