SCHEMBL28883157

SCHEMBL28883157

CC(O)CNc1cccc(Nc2ccccc2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.55
ALDH1A1 P00352 5/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
AR P10275 1/20 0.55
TSHR P16473 4/20 0.47
CYP3A4 P08684 3/20 0.47
NPSR1 Q6W5P4 1/20 0.47
HSD17B10 Q99714 5/20 0.45
LMNA P02545 4/20 0.45
MAPK1 P28482 3/20 0.45
TDP1 Q9NUW8 3/20 0.43
ALOX15 P16050 3/20 0.43
ALOX12 P18054 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
THRB P10828 1/20 0.43
RECQL P46063 1/20 0.43
ATM Q13315 1/20 0.43
KDM4E B2RXH2 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1674517 0.83 MAPT (0.58) MAPTALDH1A1LMNATDP1GAA
SCHEMBL16197831 0.83 MAPT (0.58) MAPTALDH1A1LMNATDP1GAA
SCHEMBL11448214 0.79 KDM4E (0.53) MAPTALDH1A1LMNAMAPK1TDP1
SCHEMBL4808242 0.79 ALDH1A1 (0.47) MAPTALDH1A1MEN1KMT2ATSHR
SCHEMBL11743312 0.79 MAPT (0.60) MAPTALDH1A1MEN1KMT2ACYP3A4
SCHEMBL11750105 0.77 ADRB2 (0.54) MAPTALDH1A1MEN1KMT2ATSHR
SCHEMBL20312740 0.77 GAA (0.47) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL7174664 0.77 ALDH1A1 (0.47) MAPTALDH1A1MEN1KMT2ACYP3A4
SCHEMBL14081006 0.76 RAPGEF4 (0.45) MAPTALDH1A1MEN1KMT2AMAPK1
SCHEMBL22616935 0.75 ALDH1A1 (0.41) MAPTALDH1A1MEN1KMT2AAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109153934-B Polyester dispersants, synthesis and uses thereof 雪佛龙奥伦耐有限责任公司 2022-04-05 CN disclosed