SCHEMBL28213918

SCHEMBL28213918

CS(=O)(=O)NC(=O)c1nccs1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.53
HSPA9 P38646 1/20 0.48
ACP1 P24666 2/20 0.42
GRM4 Q14833 5/20 0.42
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
NPC1 O15118 4/20 0.41
RAB9A P51151 4/20 0.41
P4HTM Q9NXG6 2/20 0.41
PPARG P37231 1/20 0.41
NCOR2 Q9Y618 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148962 0.77
SCHEMBL8592828 0.75
SCHEMBL6970218 0.73
SCHEMBL455410 0.73
SCHEMBL28503636 0.73
SCHEMBL20712728 0.73 HSPA9 (0.60) ALDH1A1HSPA9CASP3SENP8SENP7
SCHEMBL25753489 0.73 ALDH1A1 (0.55) ALDH1A1HSPA9GRM4CASP3SENP8
SCHEMBL19691137 0.73 ALDH1A1 (0.55) ALDH1A1HSPA9CASP3SENP8SENP7
SCHEMBL12124477 0.73 ALDH1A1 (0.55) ALDH1A1HSPA9GRM4CASP3SENP8
SCHEMBL28883221 0.72 ALDH1A1 (0.42) ALDH1A1HSPA9GRM4CASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103119036-B Heterocyclic Compounds as Pesticides 拜耳知识产权有限责任公司 2018-05-08 CN disclosed