Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29528616 | 0.84 | MEN1 (0.35) | KMT2AALDH1A1MEN1GABRA5GABRB2 | |
| SCHEMBL4963513 | 0.84 | MEN1 (0.39) | KMT2AALDH1A1MEN1GABRA5GABRB2 | |
| SCHEMBL13412495 | 0.80 | ALDH1A1 (0.38) | KMT2AALDH1A1MEN1GABRA5GABRB2 | |
| SCHEMBL17717276 | 0.79 | KMT2A (0.44) | KMT2AALDH1A1MEN1GABRA5GABRB2 | |
| SCHEMBL4911470 | 0.77 | KMT2A (0.39) | KMT2AALDH1A1MEN1GABRA5GABRB2 | |
| SCHEMBL28316724 | 0.76 | GABRA5 (0.32) | KMT2AALDH1A1MEN1GABRA5GABRB2 | |
| SCHEMBL29528876 | 0.76 | ALDH1A1 (0.43) | KMT2AALDH1A1MEN1GABRA5GABRB2 | |
| SCHEMBL5988033 | 0.75 | SMN1; SMN2 (0.49) | KMT2AALDH1A1MEN1GABRA5GABRB2 | |
| SCHEMBL2745279 | 0.75 | GABRA5 (0.46) | KMT2AALDH1A1MEN1GABRA5GABRB2 | |
| SCHEMBL20064050 | 0.75 | GABRA5 (0.50) | KMT2AALDH1A1MEN1GABRA5GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415358-B | 6-aminopyridin-3-ylthiazoles as ROR gamma t modulators | 詹森药业有限公司 | 2022-04-05 | — | — | CN | disclosed |