Dibenzothiophene

Dibenzothiophene

SCHEMBL28883274

CCOC(C)=O.c1ccc2c(c1)sc1ccccc12

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 1/20 0.57
GABRD O14764 1/20 0.57
GABRA1 P14867 1/20 0.57
GABRB1 P18505 1/20 0.57
GABRG2 P18507 1/20 0.57
GABRB3 P28472 1/20 0.57
GABRA5 P31644 1/20 0.57
GABRA3 P34903 1/20 0.57
GABRA2 P47869 1/20 0.57
GABRB2 P47870 1/20 0.57
GABRA4 P48169 1/20 0.57
GABRE P78334 1/20 0.57
GABRA6 Q16445 1/20 0.57
GABRG1 Q8N1C3 1/20 0.57
GABRG3 Q99928 1/20 0.57
GABRQ Q9UN88 1/20 0.57
DHODH Q02127 1/20 0.52
ALDH1A1 P00352 6/20 0.50
LMNA P02545 5/20 0.50
KMT2A Q03164 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Acetate SCHEMBL1706269 0.83 GABRP (0.46) GABRPGABRDGABRA1GABRB1GABRG2
Dibenzothiophene SCHEMBL11884108 0.78 GPR3 (0.67) ALDH1A1LMNAKMT2AHSD17B10GPR3
Phenanthrene SCHEMBL28332300 0.78 ALDH1A1 (0.54) ALDH1A1LMNAKMT2AHSD17B10MAPT
Dibenzothiophene SCHEMBL28899929 0.78 KMT2A (0.60) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL11244864 0.78 GABRP (0.60) GABRPGABRDGABRA1GABRB1GABRG2
Ethyl Acetate SCHEMBL28206231 0.78 ALDH1A1 (0.62) GABRPGABRDGABRA1GABRB1GABRG2
Dibenzothiophene SCHEMBL28857076 0.77 GPR3 (0.58) GABRPGABRDGABRA1GABRB1GABRG2
Naphthalene SCHEMBL27267438 0.77 ALDH1A1 (0.64) ALDH1A1LMNAKMT2AHSD17B10MAPT
O-Xylene SCHEMBL3225611 0.77 ALDH1A1 (0.64) DHODHALDH1A1LMNAKMT2AHSD17B10
Dibenzothiophene SCHEMBL21465288 0.76 GPR3 (0.70) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115301237-A Preparation method of iron-doped titanium dioxide photocatalytic film 中国矿业大学 2022-11-08 CN disclosed