Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883507 | 0.90 | MGLL (0.41) | MGLLATMTLR9FAAHKDM4E | |
| SCHEMBL28883378 | 0.85 | MGLL (0.42) | MGLLFAAHKDM4EALDH1A1LMNA | |
| SCHEMBL28883321 | 0.83 | MGLL (0.44) | MGLLFAAHKDM4EALDH1A1LMNA | |
| SCHEMBL28883428 | 0.83 | MGLL (0.37) | MGLLATMTSHRFAAHKDM4E | |
| SCHEMBL28883478 | 0.83 | MGLL (0.50) | MGLLTLR9TSHRFAAHKDM4E | |
| SCHEMBL28883464 | 0.82 | MGLL (0.48) | MGLLATMTLR9FAAHKDM4E | |
| SCHEMBL28883362 | 0.81 | MGLL (0.44) | MGLLTLR9FAAHKDM4EALDH1A1 | |
| SCHEMBL28883390 | 0.77 | MGLL (0.49) | MGLLTLR9FAAHALDH1A1POLB | |
| SCHEMBL28883354 | 0.77 | MGLL (0.39) | MGLLTSHRFAAHKDM4EALDH1A1 | |
| SCHEMBL28883370 | 0.74 | MGLL (0.51) | MGLLATMTLR9TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340483-A | Naphthyl pyrrolindione compound, preparation method and application thereof | 南京吉星生物技术开发有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-115340483-A | Naphthyl pyrrolindione compound, preparation method and application thereof | 南京吉星生物技术开发有限公司 | 2022-11-15 | — | — | CN | disclosed |