Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883483 | 0.84 | MGLL (0.48) | MGLLHSP90AA1TLR9ALDH1A1PKM | |
| SCHEMBL28883464 | 0.84 | MGLL (0.48) | MGLLHSP90AA1TLR9MEN1HPGD | |
| SCHEMBL28883454 | 0.83 | L3MBTL1 (0.43) | MEN1HPGDKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL28883474 | 0.83 | L3MBTL1 (0.40) | MEN1HPGDKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL28883320 | 0.82 | MGLL (0.43) | MGLLHSP90AA1HPGDALDH1A1KDM4E | |
| SCHEMBL28883380 | 0.81 | MEN1 (0.34) | MEN1HPGDKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL28883374 | 0.81 | MGLL (0.49) | MGLLHSP90AA1TLR9ALDH1A1KDM4E | |
| SCHEMBL28883417 | 0.80 | MGLL (0.44) | MGLLHSP90AA1TLR9ALDH1A1PKM | |
| SCHEMBL28883390 | 0.80 | MGLL (0.49) | MGLLHSP90AA1TLR9MEN1HPGD | |
| SCHEMBL28883507 | 0.77 | MGLL (0.41) | MGLLTLR9HPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340483-A | Naphthyl pyrrolindione compound, preparation method and application thereof | 南京吉星生物技术开发有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-115340483-A | Naphthyl pyrrolindione compound, preparation method and application thereof | 南京吉星生物技术开发有限公司 | 2022-11-15 | — | — | CN | disclosed |