Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883442 | 0.84 | MGLL (0.44) | MGLLFAAHDPP4NR1H2NR1H3 | |
| SCHEMBL28883464 | 0.80 | MGLL (0.48) | MGLLFAAHHSP90AA1TLR9NPSR1 | |
| SCHEMBL28883362 | 0.80 | MGLL (0.44) | MGLLFAAHHSP90AA1TLR9POLB | |
| SCHEMBL28883374 | 0.77 | MGLL (0.49) | MGLLFAAHHSP90AA1TLR9POLB | |
| SCHEMBL28958654 | 0.75 | MGLL (0.51) | MGLLFAAHHSP90AA1TLR9DPP4 | |
| SCHEMBL28883507 | 0.74 | MGLL (0.41) | MGLLFAAHTLR9ALDH1A1RAB9A | |
| SCHEMBL31544426 | 0.73 | MGLL (0.43) | MGLLFAAHHSP90AA1DPP4NR1H2 | |
| SCHEMBL28883404 | 0.72 | MGLL (0.44) | MGLLFAAHDPP4NR1H2NR1H3 | |
| SCHEMBL2032898 | 0.71 | MGLL (0.63) | MGLLFAAHHSP90AA1TLR9DPP4 | |
| SCHEMBL19511809 | 0.70 | TLR9 (0.54) | MGLLFAAHHSP90AA1TLR9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340483-A | Naphthyl pyrrolindione compound, preparation method and application thereof | 南京吉星生物技术开发有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-115340483-A | Naphthyl pyrrolindione compound, preparation method and application thereof | 南京吉星生物技术开发有限公司 | 2022-11-15 | — | — | CN | disclosed |