Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883474 | 0.90 | L3MBTL1 (0.40) | L3MBTL1BCL2A1HPGDALDH1A1MAPT | |
| SCHEMBL28883362 | 0.83 | MGLL (0.44) | L3MBTL1HPGDALDH1A1MAPTMAPK1 | |
| SCHEMBL28883380 | 0.81 | MEN1 (0.34) | L3MBTL1HPGDALDH1A1MAPTPOLB | |
| SCHEMBL28883344 | 0.77 | TSHR (0.44) | L3MBTL1ALDH1A1POLBTSHRKMT2A | |
| SCHEMBL28883411 | 0.75 | TNF (0.37) | L3MBTL1ALDH1A1MAPTPOLBTSHR | |
| SCHEMBL7557507 | 0.72 | L3MBTL1 (0.44) | L3MBTL1MAPTTSHRMEN1KMT2A | |
| SCHEMBL7556780 | 0.72 | L3MBTL1 (0.65) | L3MBTL1HPGDALDH1A1MAPTMAPK1 | |
| SCHEMBL11610829 | 0.72 | L3MBTL1 (0.55) | L3MBTL1BCL2A1ALDH1A1POLBMEN1 | |
| SCHEMBL28883360 | 0.70 | MEN1 (0.38) | L3MBTL1HPGDMAPTPOLBMEN1 | |
| SCHEMBL29720333 | 0.68 | CYP2A6 (0.48) | L3MBTL1HPGDALDH1A1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340483-A | Naphthyl pyrrolindione compound, preparation method and application thereof | 南京吉星生物技术开发有限公司 | 2022-11-15 | — | — | CN | disclosed |