Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.40 |
| ▸ | XDH | P47989 | 3/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 5/20 | 0.38 |
| ▸ | PI4KA | P42356 | 4/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1831279 | 0.84 | XDH (0.50) | XDHSTING1MEN1ALDH1A1LMNA | |
| SCHEMBL580610 | 0.75 | ADORA2A (0.64) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL28413958 | 0.73 | ADORA2A (0.62) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL27773184 | 0.72 | ADORA2A (0.43) | ADORA2AADORA1STING1PI4KAPI4K2B | |
| SCHEMBL28410735 | 0.72 | ADORA2A (0.60) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| Adenine SCHEMBL28949703 | 0.72 | PNP (0.42) | ADORA2AADORA1XDHMEN1ALDH1A1 | |
| SCHEMBL23365318 | 0.71 | ADORA2A (0.43) | ADORA2AADORA1MEN1ALDH1A1CYP3A4 | |
| SCHEMBL986800 | 0.71 | XDH (0.60) | XDHMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL3474052 | 0.70 | ADORA2A (0.44) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL15005119 | 0.70 | XDH (0.59) | XDHMEN1ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105264091-B | Compositions and methods for modulating TAU expression | IONIS制药公司 | 2020-02-28 | — | — | CN | disclosed |