Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 11/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 10/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 10/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 10/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 10/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2352519 | 0.82 | PNP (0.43) | ADORA2AADORA2B | |
| SCHEMBL1831279 | 0.79 | XDH (0.50) | STING1 | |
| SCHEMBL72147 | 0.79 | XDH (0.50) | — | |
| SCHEMBL580610 | 0.78 | ADORA2A (0.64) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL1426626 | 0.77 | FDPS (0.34) | — | |
| SCHEMBL28413958 | 0.77 | ADORA2A (0.62) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL3474052 | 0.76 | ADORA2A (0.44) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL8820865 | 0.75 | ADORA2A (0.46) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL28410735 | 0.75 | ADORA2A (0.60) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL2558880 | 0.72 | PI4KA (0.44) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109328237-B | Inhibitors of PAPD5 and PAPD7 for the treatment of hepatitis b infection | 豪夫迈·罗氏有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-107849584-A | The electrochemica biological reactor module and engineering metabolic pathway of 1 butanol are produced with high carbon efficiencies | 百奥堪引赛股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-101507765-B | Medicine for treating cerebrovascular disease and sequela thereof and preparation method thereof | XIAOFEI DU | 2011-03-23 | — | — | CN | disclosed |
| CN-101507765-A | Medicine for treating cerebrovascular disease and sequela thereof and preparation method thereof | XIAOFEI DU (CN) | 2009-08-19 | — | — | CN | disclosed |