SCHEMBL28887343

SCHEMBL28887343

[CH2]CCCCCCCCOc1ccc(-c2ccc(C#N)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.58
HDAC2 Q92769 1/20 0.58
MMP3 P08254 5/20 0.56
MMP2 P08253 5/20 0.55
HRH3 Q9Y5N1 10/20 0.55
HRH2 P25021 8/20 0.55
HRH1 P35367 8/20 0.55
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 2/20 0.51
HPGD P15428 2/20 0.51
MMP1 P03956 1/20 0.51
MMP9 P14780 1/20 0.51
MMP13 P45452 1/20 0.51
HTT P42858 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16798363 1.00 HDAC1 (0.58) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL9852404 0.98 MMP3 (0.57) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL9653965 0.93 MMP2 (0.58) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL22645668 0.93 HRH3 (0.54) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL16841044 0.91 HDAC1 (0.67) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL29444063 0.91 HDAC1 (0.67) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL18079151 0.91 HDAC1 (0.67) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL26602050 0.89 MMP3 (0.66) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL28388624 0.87 MMP2 (0.60) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL2779902 0.87 HRH3 (0.53) HDAC1HDAC2MMP3MMP2HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108218797-B Liquid crystal molecule modified pyrimidine diamine monomer, liquid crystal orientation material derived from same and synthesis method thereof 同济大学 2020-03-17 CN claimed
CN-108218797-B Liquid crystal molecule modified pyrimidine diamine monomer, liquid crystal orientation material derived from same and synthesis method thereof 同济大学 2020-03-17 CN disclosed