Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PER2 | O15055 | 2/20 | 0.37 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28395634 | 0.85 | TACR1 (0.51) | TACR1KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL28888717 | 0.84 | MAT2A (0.41) | TACR1KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL5094690 | 0.84 | HTR6 (0.44) | TACR1MAPTPER2CRY2JAK2 | |
| Hydrochloric Acid SCHEMBL5094866 | 0.83 | HTR6 (0.43) | TACR1MAPTPER2CRY2JAK2 | |
| SCHEMBL28390633 | 0.83 | RAB9A (0.41) | TACR1KDM4EMAPTMAPK1MEN1 | |
| SCHEMBL28395787 | 0.82 | KMT2A (0.40) | TACR1KDM4EMAPTL3MBTL1PER2 | |
| Oxalic Acid SCHEMBL5094982 | 0.79 | TACR1 (0.43) | TACR1KDM4EMAPTPTGDRPTGDR2 | |
| Dimethylamine SCHEMBL5095643 | 0.79 | PTPN1 (0.39) | TACR1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL5095599 | 0.78 | TACR1 (0.41) | TACR1PER2CRY2PTGDRPTGDR2 | |
| SCHEMBL5767302 | 0.78 | TACR1 (0.40) | TACR1PER2CRY2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556320-B | Method for synthesizing 6H-isoindolo [2,1-a ] indol-6-one derivative | 复旦大学 | 2020-05-12 | — | — | CN | disclosed |