Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28395634 | 0.85 | TACR1 (0.51) | TACR1MAPTL3MBTL1LMNAKDM4E | |
| SCHEMBL28888365 | 0.84 | TACR1 (0.41) | TACR1MAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL5089907 | 0.84 | HTR6 (0.44) | MAT2AMTNR1AMTNR1BTACR1MAPT | |
| SCHEMBL28390633 | 0.83 | RAB9A (0.41) | TACR1MAPTCYP1A2CYP3A4CYP2C9 | |
| Dimethylamine SCHEMBL5095643 | 0.79 | PTPN1 (0.39) | MTNR1AMTNR1BTACR1MAPTCYP1A2 | |
| SCHEMBL28717894 | 0.77 | ACLY (0.43) | L3MBTL1DNMT1LMNAKDM4EMAPK1 | |
| SCHEMBL5089912 | 0.74 | NTRK1 (0.38) | MAT2AMAPTL3MBTL1DNMT1LMNA | |
| SCHEMBL5101581 | 0.72 | NTRK1 (0.40) | MAT2ACYP1A2CYP3A4NTRK1 | |
| SCHEMBL5101582 | 0.72 | MAT2A (0.39) | MAT2AMTNR1AMTNR1BTACR1MAPT | |
| SCHEMBL5101584 | 0.72 | NTRK1 (0.40) | MAT2ACYP1A2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556320-B | Method for synthesizing 6H-isoindolo [2,1-a ] indol-6-one derivative | 复旦大学 | 2020-05-12 | — | — | CN | disclosed |