Chloralin

Chloralin

SCHEMBL28889062

FC(F)(F)c1ccc(Cl)cc1.O=[N+]([O-])c1cc(C(F)(F)F)cc([N+](=O)[O-])c1Cl

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.80
ALDH1A1 P00352 2/20 0.80
CYP3A4 P08684 2/20 0.80
TDP1 Q9NUW8 2/20 0.80
HPGD P15428 1/20 0.80
ALOX15 P16050 1/20 0.80
HIF1A Q16665 1/20 0.80
TXNRD1 Q16881 1/20 0.80
TXNRD3 Q86VQ6 1/20 0.80
TXNRD2 Q9NNW7 1/20 0.80
FLT1 P17948 1/20 0.52
FLT4 P35916 1/20 0.52
KDR P35968 1/20 0.52
EPAS1 Q99814 1/20 0.49
LMNA P02545 5/20 0.48
MAPT P10636 5/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
HTT P42858 3/20 0.48
GAA P10253 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloralin SCHEMBL455937 0.89 CYP3A4 (1.00) TSHRALDH1A1CYP3A4TDP1HPGD
SCHEMBL7819749 0.81 ALDH1A1 (0.82) TSHRALDH1A1CYP3A4TDP1HPGD
SCHEMBL11343876 0.79 ALDH1A1 (0.79) TSHRALDH1A1CYP3A4TDP1HPGD
SCHEMBL10414958 0.79 CYP3A4 (0.79) TSHRALDH1A1CYP3A4TDP1HPGD
SCHEMBL10862632 0.78 ALDH1A1 (0.77) TSHRALDH1A1CYP3A4TDP1HPGD
SCHEMBL9649686 0.78 CYP3A4 (0.77) TSHRALDH1A1CYP3A4TDP1HPGD
SCHEMBL17680884 0.78 CYP3A4 (0.77) TSHRALDH1A1CYP3A4TDP1HPGD
SCHEMBL140068 0.77 ALDH1A1 (0.65) TSHRALDH1A1CYP3A4TDP1HPGD
SCHEMBL10587400 0.77 MAPT (0.57) TSHRALDH1A1CYP3A4TDP1HPGD
Dinitrophenylene SCHEMBL27873807 0.77 ALDH1A1 (0.58) TSHRALDH1A1CYP3A4TDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111205187-A Preparation method of 4-chloro-3, 5-dinitrobenzotrifluoride 内蒙古大中实业化工有限公司 2020-05-29 CN disclosed