SCHEMBL140068

SCHEMBL140068

O=[N+]([O-])c1cc(C(F)(F)F)ccc1Cl

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.65
CYP3A4 P08684 2/20 0.65
TDP1 Q9NUW8 2/20 0.65
HPGD P15428 1/20 0.65
ALOX15 P16050 1/20 0.65
TSHR P16473 1/20 0.65
HIF1A Q16665 1/20 0.65
TXNRD1 Q16881 1/20 0.65
TXNRD3 Q86VQ6 1/20 0.65
TXNRD2 Q9NNW7 1/20 0.65
EPAS1 Q99814 1/20 0.52
VCAM1 P19320 4/20 0.51
MAPK1 P28482 3/20 0.50
MAPT P10636 4/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
LMNA P02545 2/20 0.49
POLB P06746 1/20 0.49
XBP1 P17861 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitric Acid SCHEMBL11801208 0.95 ALDH1A1 (0.59) ALDH1A1CYP3A4TDP1HPGDALOX15
Nitric Acid SCHEMBL11801207 0.95 ALDH1A1 (0.59) ALDH1A1CYP3A4TDP1HPGDALOX15
SCHEMBL7218755 0.89 TDP1 (0.55) ALDH1A1CYP3A4TDP1HPGDALOX15
Toluene SCHEMBL8006523 0.88 MAPK1 (0.54) ALDH1A1CYP3A4TDP1HPGDALOX15
SCHEMBL8569064 0.86 ALDH1A1 (0.53) ALDH1A1CYP3A4TDP1HPGDALOX15
SCHEMBL29446908 0.85 TDP1 (0.59) ALDH1A1CYP3A4TDP1HPGDALOX15
SCHEMBL6080 0.85 TDP1 (0.59) ALDH1A1CYP3A4TDP1HPGDALOX15
SCHEMBL10907199 0.83 VCAM1 (0.53) ALDH1A1CYP3A4TDP1HPGDALOX15
SCHEMBL28418924 0.83 TDP1 (0.49) ALDH1A1CYP3A4TDP1HPGDALOX15
SCHEMBL8229723 0.83 MAPT (0.57) ALDH1A1CYP3A4TDP1HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 893 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115850082-B Preparation method of 2-nitro-4-trifluoromethyl benzoic acid 内蒙古蓝科生物科技有限公司 2025-05-06 CN claimed
CN-119270036-B Communication method of chip tester based on PCIE multi-machine cascade and route 杭州高坤电子科技有限公司 2025-03-25 CN claimed
CN-117658818-B Preparation method of 4-fluoro-3-nitrobenzotrifluoride 江西巍华化学有限公司 2025-02-07 CN claimed
CN-119270036-A Communication method of chip tester based on PCIE multi-machine cascade and route 杭州高坤电子科技有限公司 2025-01-07 CN claimed
CN-118837745-A NMC battery jump point online early warning method and system based on hybrid mechanism model 华中科技大学 2024-10-25 CN claimed
CN-118702576-A Process for improving yield of 4-chloro-3, 5-dinitrobenzotrifluoride 福建康峰新材料有限公司 2024-09-27 CN claimed
CN-118616072-A Ni/NC catalyst and application thereof in preparation of 4-chloro-3-aminotrifluorotoluene 浙江巍华新材料股份有限公司 2024-09-10 CN claimed
CN-113283099-B Modeling method of wind-solar hydrogen storage sea water desalination system 国网辽宁省电力有限公司 2024-08-16 CN claimed
CN-118403473-A Gas-water separation membrane framework, normal pressure VOCs self-breathing gas proton separation membrane and application thereof 辽宁东德恩环保科技有限公司 2024-07-30 CN claimed
CN-118271176-A Preparation method of 4-chloro-3, 5-dinitrobenzotrifluoride 江西巍华化学有限公司 2024-07-02 CN claimed
CN-1184191-C Fluoro substituted diphenylamine devirant ZHEJIANG PROVINCIAL INST OF CH (CN) 2005-01-12 CN claimed
CN-1333205-A Fluoro substituted diphenylamine devirant ZHEJIANG PROVINCIAL INST OF CH (CN) 2002-01-30 CN claimed
US-5728881-A Process for preparing trifluralin SRM CHEMICAL, LTD. CO. (US) 1998-03-17 US claimed
EP-0381010-A2 Process for the preparation of 2-nitro-4-trifluoromethyl aniline HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-08 EP claimed
EP-0138302-B1 PYRAZOLO(3,4,5-KL)ACRIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND PROCESSES FOR THEIR PRODUCTION WARNER-LAMBERT COMPANY (US) 1988-03-09 EP claimed
US-4413126-A TRIFLUOROMETHYL SUBSTITUTED 1H-BENZIMIDAZO(2,1-A)BENZ(DE)ISOQUINOLIN-7-ONE ELI LILLY AND COMPANY (US) 1983-11-01 US claimed
EP-0004623-B1 PROCESS FOR THE PREPARATION OF AROMATIC AMINES BAYER AG (DE) 1981-07-01 EP claimed
US-4175186-A CYCLIZATION OF A NITROHALOBENZENE COMPOUND WITH A DIALKYDITHIOCARBAMIC ACID THE ANSUL COMPANY (US) 1979-11-20 US claimed
US-4096195-A Cyclic two-stage nitration process for preparing 4-chloro-3,5-dinitrobenzotrifluoride from 4-chlorobenzotrifluoride GAF CORPORATION (US) 1978-06-20 US claimed
US-3984488-A Dinitration of nitrobenzotrifluoride AIR PRODUCTS AND CHEMICALS, INC. (US) 1976-10-05 US claimed