Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 11/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 2/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941803 | 0.89 | HDAC4 (0.42) | HDAC4HDAC3HDAC7HDAC8HDAC6 | |
| SCHEMBL28889187 | 0.89 | MEN1 (0.40) | LMNAMEN1KMT2AADRB2 | |
| SCHEMBL28889281 | 0.89 | KMT2A (0.40) | LMNAMEN1KMT2AADRB2P2RY1 | |
| SCHEMBL28889319 | 0.88 | ADRB2 (0.41) | MEN1KMT2AADRB2 | |
| SCHEMBL28959166 | 0.88 | MEN1 (0.41) | LMNAMEN1KMT2AADRB2P2RY1 | |
| SCHEMBL28889382 | 0.86 | ADRB2 (0.39) | LMNAMEN1KMT2AADRB2P2RY1 | |
| SCHEMBL29941971 | 0.85 | HDAC4 (0.41) | HDAC4HDAC3HDAC7HDAC8HDAC6 | |
| SCHEMBL29942164 | 0.85 | HDAC4 (0.41) | HDAC4HDAC3HDAC7HDAC8HDAC6 | |
| SCHEMBL29941697 | 0.85 | MEN1 (0.49) | MEN1KMT2AADRB2 | |
| SCHEMBL28889336 | 0.84 | HDAC4 (0.41) | HDAC4HDAC3HDAC7HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022222911-A1 | PYRIMIDONE COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-10-27 | — | — | WO | disclosed |
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |