Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.34 |
| ▸ | CBLB | Q13191 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29894640 | 1.00 | HDAC4 (0.40) | HDAC4HDAC7HDAC5ADRB2OPRM1 | |
| SCHEMBL28889194 | 0.90 | ADRB2 (0.37) | ADRB2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL28889250 | 0.85 | MEN1 (0.44) | HDAC4HDAC7HDAC5ADRB2OPRM1 | |
| SCHEMBL28889237 | 0.85 | ADRB2 (0.39) | ADRB2ALDH1A1L3MBTL1P2RY1MAPT | |
| SCHEMBL29893755 | 0.85 | MEN1 (0.44) | HDAC4HDAC7HDAC5ADRB2OPRM1 | |
| SCHEMBL29941818 | 0.83 | HDAC4 (0.41) | HDAC4HDAC7HDAC5ADRB2OPRM1 | |
| SCHEMBL28889336 | 0.83 | HDAC4 (0.41) | HDAC4HDAC7HDAC5ADRB2ALDH1A1 | |
| SCHEMBL28889204 | 0.82 | ADRB2 (0.39) | ADRB2ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28959159 | 0.81 | ADRB2 (0.38) | HDAC4HDAC7HDAC5ADRB2ALDH1A1 | |
| SCHEMBL28889308 | 0.81 | ADRB2 (0.38) | ADRB2ALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |