Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29894334 | 1.00 | KMT2A (0.38) | KMT2AGHSRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29942343 | 0.90 | KMT2A (0.39) | KMT2AGHSRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28889252 | 0.88 | PKM (0.41) | KMT2AGHSRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29893701 | 0.88 | PKM (0.41) | KMT2AGHSRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28889188 | 0.85 | ADRB2 (0.39) | KMT2AGHSRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL29893847 | 0.78 | GLA (0.39) | KMT2AGHSRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28889231 | 0.78 | GLA (0.39) | KMT2AGHSRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29941823 | 0.75 | ADRB2 (0.40) | KMT2AGHSRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28889346 | 0.75 | CTSA (0.42) | KMT2ASMN1; SMN2ALDH1A1LMNAPOLB | |
| SCHEMBL28889319 | 0.73 | ADRB2 (0.41) | KMT2AGHSRSMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |