Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893847 | 1.00 | GLA (0.39) | GLAHPGDOPRL1ALDH1A1KMT2A | |
| SCHEMBL28889221 | 0.81 | ADRB2 (0.41) | GLAHPGDOPRL1ALDH1A1KMT2A | |
| SCHEMBL28889252 | 0.81 | PKM (0.41) | GLAHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL29893701 | 0.81 | PKM (0.41) | GLAHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL29942343 | 0.80 | KMT2A (0.39) | GLAHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL28889262 | 0.78 | KMT2A (0.38) | GLAHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL29894334 | 0.78 | KMT2A (0.38) | GLAHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL28889313 | 0.75 | ALDH1A1 (0.52) | GLAHPGDALDH1A1GAARAB9A | |
| SCHEMBL29894007 | 0.75 | ALDH1A1 (0.52) | GLAHPGDALDH1A1GAARAB9A | |
| SCHEMBL19552356 | 0.69 | ALOX5AP (0.38) | OPRL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |