Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893701 | 1.00 | PKM (0.41) | PKMKMT2AMEN1GHSRSMN1; SMN2 | |
| SCHEMBL29942343 | 0.90 | KMT2A (0.39) | PKMKMT2AMEN1GHSRSMN1; SMN2 | |
| SCHEMBL29894334 | 0.88 | KMT2A (0.38) | PKMKMT2AMEN1GHSRSMN1; SMN2 | |
| SCHEMBL28889262 | 0.88 | KMT2A (0.38) | PKMKMT2AMEN1GHSRSMN1; SMN2 | |
| SCHEMBL28889319 | 0.84 | ADRB2 (0.41) | PKMKMT2AMEN1GHSRSMN1; SMN2 | |
| SCHEMBL29893847 | 0.81 | GLA (0.39) | KMT2AMEN1GHSRSMN1; SMN2KDM4E | |
| SCHEMBL28889231 | 0.81 | GLA (0.39) | KMT2AMEN1GHSRSMN1; SMN2KDM4E | |
| SCHEMBL29941704 | 0.78 | ADRB2 (0.39) | PKMKMT2AMEN1GHSRALDH1A1 | |
| SCHEMBL29941823 | 0.74 | ADRB2 (0.40) | KMT2AMEN1GHSRSMN1; SMN2KDM4E | |
| SCHEMBL28889189 | 0.73 | CTSA (0.45) | KMT2AMEN1SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |