Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29785325 | 1.00 | ALOX12 (0.53) | ALOX12ALDH1A1CES1HTR2CPTGER4 | |
| SCHEMBL9789155 | 0.69 | ALOX12 (0.64) | ALOX12ALDH1A1CES1L3MBTL1ATM | |
| SCHEMBL8554742 | 0.67 | ALOX12 (0.66) | ALOX12ALDH1A1CES1HTR2CL3MBTL1 | |
| SCHEMBL29933410 | 0.66 | ALDH1A1 (0.60) | ALOX12ALDH1A1SIGMAR1SMN1; SMN2 | |
| SCHEMBL1437753 | 0.66 | ALDH1A1 (0.60) | ALOX12ALDH1A1SIGMAR1SMN1; SMN2 | |
| SCHEMBL9789127 | 0.64 | ALOX12 (0.50) | ALOX12ALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL5410892 | 0.62 | ALDH1A1 (0.54) | ALOX12ALDH1A1SIGMAR1SMN1; SMN2 | |
| SCHEMBL9827964 | 0.61 | ALOX12 (0.40) | ALOX12ALDH1A1CES1HTR2CPTGER4 | |
| SCHEMBL28555654 | 0.60 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1ATMKDM4EHPGD | |
| SCHEMBL9015889 | 0.59 | ALOX12 (0.41) | ALOX12ALDH1A1CES1PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111217724-B | Ortho-alkylated electron-rich arylamine and preparation method and application thereof | 广东工业大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-111217724-A | Ortho-alkylated electron-rich arylamine and preparation method and application thereof | 广东工业大学 | 2020-06-02 | — | — | CN | disclosed |