SCHEMBL276503

SCHEMBL276503

NOP(=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
CA2 P00918 2/20 0.46
CA4 P22748 1/20 0.46
CA5A P35218 1/20 0.46
TDP1 Q9NUW8 1/20 0.44
LMNA P02545 2/20 0.42
RECQL P46063 1/20 0.42
CFTR P13569 1/20 0.41
GAA P10253 2/20 0.39
MAPT P10636 1/20 0.39
ALPG P10696 1/20 0.39
ALOX12 P18054 1/20 0.39
NPY1R P25929 1/20 0.39
HTT P42858 1/20 0.39
NPY2R P49146 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TSHR P16473 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL15313341 0.97 ALDH1A1 (0.56) ALDH1A1L3MBTL1MEN1KMT2ACA2
Iodide SCHEMBL15313340 0.95 ALDH1A1 (0.54) ALDH1A1L3MBTL1MEN1KMT2ACA2
SCHEMBL28890291 0.83 ALDH1A1 (0.47) ALDH1A1L3MBTL1MEN1KMT2ACA2
SCHEMBL28492227 0.80 ALDH1A1 (0.48) ALDH1A1L3MBTL1MEN1KMT2ACA2
SCHEMBL10608636 0.79 L3MBTL1 (0.56) ALDH1A1L3MBTL1MEN1KMT2ACA2
SCHEMBL29086939 0.79 CA2 (0.52) ALDH1A1L3MBTL1MEN1KMT2ACA2
SCHEMBL7277887 0.78 ALDH1A1 (0.56) ALDH1A1L3MBTL1MEN1KMT2ACA2
SCHEMBL5877657 0.78 ALDH1A1 (0.56) ALDH1A1L3MBTL1MEN1KMT2ACA2
SCHEMBL27494600 0.76 ALDH1A1 (0.54) ALDH1A1L3MBTL1MEN1KMT2ACA2
SCHEMBL18951487 0.75 L3MBTL1 (0.48) ALDH1A1L3MBTL1MEN1KMT2ACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1067 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025073057-A1 METHODS FOR PREPARING SULFILIMINES AND SULFOXIMINES FROM THIOETHERS USING O-(DIPHENYLPHOSPHINYL)HYDROXYL AMINE (DPPH), AND AMATOXIN ANALOGS PREPARED FROM SUCH METHODS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2025-04-10 WO claimed
CN-117069063-A Sodium hydride suspension and application thereof in flow chemical reaction 武汉药明康德新药开发有限公司 2023-11-17 CN claimed
CN-112552339-A Preparation method of O-diphenylphosphoryl hydroxylamine 安徽昊帆生物有限公司 2021-03-26 CN claimed
US-20060264624-A1 Methods for synthesizing imidazotriazinones LEXICON GENETICS INCORPORATED 2006-11-23 US claimed
WO-2026104680-A1 NOVEL SULFONAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-05-21 WO disclosed
WO-2026104681-A1 NEW SULFONAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-05-21 WO disclosed
WO-2026104678-A1 NOVEL SULFONAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-05-21 WO disclosed
EP-4745134-A1 PROTEIN ARGINASE METHYLTRANSFERASE-5 INHIBITOR AND MEDICAL USE THEREOF Jiangsu Yahong Meditech Co., Ltd. (CN) 2026-05-20 EP disclosed
US-20260132136-A1 Pyrazolo[5,1-f][1,2,4]triazin-4-ones as inhibitors of NOX4 BOEHRINGER INGELHEIM INT GMBH (DE) 2026-05-14 US disclosed
EP-4211119-B1 2-AMINOQUINAZOLINES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF MERCK SHARP & DOHME LLC (US) 2026-05-13 EP disclosed
EP-4739690-A1 SUBSTITUTED QUINOLYL/QUINOXALYL DIHYDROPYRROLOTRIAZINE COMPOUNDS FOR COMBATTING PHYTO-PATHOGENIC FUNGI BASF SE (DE) 2026-05-13 EP disclosed
EP-4739691-A1 SUBSTITUTED PYRIDYL/PYRAZINYL DIHYDROPYRROLOTRIAZINE COMPOUNDS FOR COMBATTING PHYTOPATH-OGENIC FUNGI BASF SE (DE) 2026-05-13 EP disclosed
EP-0292191-A1 2-(Substituted methyl)-1-alkylcarbapenem derivatives MERCK & CO. INC. (US) 1988-11-23 EP disclosed
EP-0266532-A1 1,3-Disubstituted imidazolium salts F. HOFFMANN-LA ROCHE AG (CH) 1988-05-11 EP disclosed
EP-0253084-A2 1,3-Disubstituted imidazolium salts F. HOFFMANN-LA ROCHE AG (CH) 1988-01-20 EP disclosed
EP-0200947-A1 1,3-Disubstituted imidazolium salts F. HOFFMANN-LA ROCHE AG (CH) 1986-11-12 EP disclosed
EP-0181926-A1 SUBSTITUTED CUBANES UNIVERSITY PATENTS, INC. (US) 1986-05-28 EP disclosed
WO-1985005357-A1 SUBSTITUTED CUBANES UNIVERSITY PATENTS, INC. (US) 1985-12-05 WO disclosed
US-4539148-A OXYGENATED BUTYRIC ACID DERIVATIVES OF OXOAZETIDINE SHIONOGI & CO., LTD. (JP) 1985-09-03 US disclosed
EP-0102893-A1 A novel production of 1-oxacephams SHIONOGI & CO., LTD. (JP) 1984-03-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132136-A1 Pyrazolo[5,1-f][1,2,4]triazin-4-ones as inhibitors of NOX4 NOX4, NOX1, NOX3 ALDH1A1 161/4885L3MBTL1 3608/4885MEN1 4824/4885
US-20060264624-A1 Methods for synthesizing imidazotriazinones PDE3A, PDE2A, PDE3B ALDH1A1 1422/4885L3MBTL1 4829/4885MEN1 2618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.