Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755233 | 0.81 | TDP1 (0.40) | CA2KMT2ASMN1; SMN2 | |
| SCHEMBL7252825 | 0.69 | ALDH1A1 (0.42) | CA2ALDH1A1RAB9ASLC6A3KDM4E | |
| SCHEMBL28567390 | 0.67 | CA2 (0.39) | CA2ALDH1A1SLC6A3MAPTKMT2A | |
| SCHEMBL31650964 | 0.65 | ALDH1A1 (0.56) | CA2ALDH1A1RAB9ASLC6A3KDM4E | |
| SCHEMBL15529908 | 0.64 | — | — | |
| Pemoline Dione SCHEMBL7864463 | 0.64 | CA2 (1.00) | CA2ALDH1A1RAB9ASLC6A3KDM4E | |
| SCHEMBL28790257 | 0.64 | CA2 (0.50) | CA2ALDH1A1RAB9ASLC6A3KDM4E | |
| SCHEMBL983728 | 0.63 | ALDH1A1 (0.54) | CA2ALDH1A1RAB9ASLC6A3KDM4E | |
| SCHEMBL28452557 | 0.63 | ALDH1A1 (0.54) | CA2ALDH1A1RAB9ASLC6A3KDM4E | |
| Pemoline Dione SCHEMBL11265294 | 0.63 | CA2 (0.96) | CA2ALDH1A1RAB9ASLC6A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295383-A | Benzoxazine derivatives useful as monoacylglycerol lipase inhibitors | 豪夫迈·罗氏有限公司 | 2020-06-16 | — | — | CN | disclosed |