Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 18/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28411950 | 0.83 | SYK (0.43) | SYKKCNH2CYP2D6 | |
| SCHEMBL28416834 | 0.77 | SYK (0.42) | SYKKCNH2CYP2D6 | |
| SCHEMBL28477215 | 0.74 | ILK (0.49) | SYKLRRK2CYP2D6 | |
| SCHEMBL29084254 | 0.74 | TYK2 (0.51) | SYK | |
| SCHEMBL29084261 | 0.74 | JAK2 (0.46) | SYKKCNH2 | |
| SCHEMBL29084256 | 0.74 | SYK (0.57) | SYKKCNH2 | |
| SCHEMBL29084257 | 0.73 | SYK (0.39) | SYKKCNH2LRRK2 | |
| SCHEMBL28416816 | 0.73 | NPC1 (0.42) | SYKKCNH2 | |
| SCHEMBL28413940 | 0.72 | NNMT (0.43) | SYKKCNH2 | |
| SCHEMBL28485231 | 0.69 | SMN1; SMN2 (0.48) | SYKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315737-A | Sulfonylpyridinylalkylamide substituted heteroaryl compounds | 百时美施贵宝公司 | 2020-06-19 | — | — | CN | claimed |
| CN-111315737-B | Heteroaryl compounds substituted with sulfone pyridinylalkylamides | 百时美施贵宝公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-111315737-A | Sulfonylpyridinylalkylamide substituted heteroaryl compounds | 百时美施贵宝公司 | 2020-06-19 | — | — | CN | disclosed |