Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LATS1 | O95835 | 1/20 | 0.37 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2785385 | 0.83 | KCNA5 (0.40) | LMNACYP19A1LTA4H | |
| SCHEMBL2888778 | 0.78 | LMNA (0.32) | LMNAIDO1AGXT | |
| SCHEMBL27832092 | 0.73 | KIF11 (0.38) | USP2RAB9ACYP19A1 | |
| SCHEMBL6182586 | 0.71 | LOXL2 (0.38) | USP2RAB9ASMN1; SMN2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1533248 | 0.69 | LOXL2 (0.37) | USP2RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11682260 | 0.69 | USP2 (0.52) | USP2RAB9ALATS1LATS2CYP17A1 | |
| SCHEMBL1505807 | 0.69 | CYP1A2 (0.48) | SMN1; SMN2LMNALTA4H | |
| SCHEMBL20492582 | 0.67 | KCNN4 (0.36) | USP2RAB9AL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6164152 | 0.67 | USP2 (0.58) | USP2RAB9AL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7439189 | 0.67 | USP2 (0.58) | USP2RAB9AL3MBTL1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102408413-B | Anticoccidial compound, and preparation method and use thereof | CHINA ANIMAL HUSBANDRY INDUSTRY CO LTD | 2013-08-14 | — | — | CN | disclosed |
| CN-102311425-B | Anticoccidiosis compound and preparation method as well as application thereof | CHINA ANIMAL HUSBANDRY INDUSTRY CO LTD | 2013-06-05 | — | — | CN | disclosed |
| CN-102408413-A | Anticoccidial compound and preparation method and application thereof | CHINA ANIMAL HUSBANDRY INDUSTRY CO LTD | 2012-04-11 | — | — | CN | disclosed |
| CN-102311425-A | Anticoccidiosis compound and preparation method as well as application thereof | CHINA ANIMAL HUSBANDRY INDUSTRY CO LTD | 2012-01-11 | — | — | CN | disclosed |
| US-8084395-B2 | 4-aza indole derivatives and their use as fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100184598-A1 | 4-AZA INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-07-22 | — | — | US | disclosed |
| CN-101784191-A | 4-aza indole derivatives and their use as fungicides | SYNGENTA PARTICIPATIONS AG | 2010-07-21 | — | — | CN | disclosed |
| EP-2136640-A2 | 4-AZA INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | Syngeta Participations AG (CH) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008132434-A2 | 4-AZA INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-11-06 | — | — | WO | disclosed |
| EP-1508569-A2 | Process for the preparation of tetrasubstituted imidazole derivatives and novel crystalline structures thereof | Ortho-McNeil Pharmaceutical, Inc. (US) | 2005-02-23 | — | — | EP | disclosed |
| EP-1506966-A2 | Process for the preparation of tetrasubstituted imidazole derivatives and novel crystaline structures thereof | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2005-02-16 | — | — | EP | disclosed |
| EP-1392678-A2 | PROCESS FOR THE PREPARATION OF TETRASUBSTITUTED IMIDAZOLE DERIVATIVES AND NOVEL CRYSTALLINE STRUCTURES THEREOF | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002076974-A2 | PROCESS FOR THE PREPARATION OF TETRASUBSTITUTED IMIDAZOLE DERIVATIVES AND NOVEL CRYSTALLINE STRUCTURES THEREOF | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184598-A1 | 4-AZA INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | IDO1, INMT, AZI2 | USP2 3896/4885RAB9A 1774/4885LATS1 1909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.