Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 7/20 | 0.32 |
| ▸ | KDM1A | O60341 | 8/20 | 0.32 |
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | POU2F2 | P09086 | 1/20 | 0.31 |
| ▸ | POU2F1 | P14859 | 1/20 | 0.31 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28422546 | 0.81 | S1PR1 (0.35) | — | |
| SCHEMBL28540951 | 0.73 | MCHR1 (0.34) | — | |
| SCHEMBL28427006 | 0.69 | PDE2A (0.38) | — | |
| SCHEMBL22129389 | 0.68 | RET (0.37) | RETKCNJ1 | |
| SCHEMBL25786963 | 0.67 | MBOAT4 (0.37) | MBOAT4 | |
| SCHEMBL25537805 | 0.66 | CTSK (0.41) | MBOAT4 | |
| SCHEMBL28910792 | 0.64 | KCNH2 (0.42) | MBOAT4KCNH2 | |
| SCHEMBL22153061 | 0.62 | PDE9A (0.41) | RET | |
| SCHEMBL23486603 | 0.62 | KDM1A (0.35) | KDM1AMBOAT4 | |
| SCHEMBL22153065 | 0.62 | JAK2 (0.36) | RETKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111333626-A | Phenyl pyrrolidine compounds and uses thereof | 湖北生物医药产业技术研究院有限公司 | 2020-06-26 | — | — | CN | disclosed |