Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 2/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Warburganal SCHEMBL4244667 | 1.00 | CHRNB2 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| Warburganal SCHEMBL13855683 | 1.00 | CHRNB2 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| SCHEMBL11130748 | 0.84 | PDE4D (0.45) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| Mukaadial SCHEMBL20462894 | 0.73 | EDNRB (0.34) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| Mukaadial SCHEMBL21025699 | 0.73 | EDNRB (0.34) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| Cinnamodial SCHEMBL15557354 | 0.68 | EDNRB (0.41) | TRPM2PLA2G2AEPAS1MAPT | |
| Cinnamodial SCHEMBL20462860 | 0.68 | EDNRB (0.41) | TRPM2PLA2G2AEPAS1MAPT | |
| SCHEMBL28263671 | 0.62 | CHRNB2 (0.64) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| SCHEMBL29751910 | 0.62 | CHRNB2 (0.64) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| Polygodial SCHEMBL258239 | 0.62 | CHRNB2 (1.00) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12478091-B2 | Vaporizable alkaloid compositions and methods of use thereof | Ready Mix Naturals, LLC (US) | 2025-11-25 | — | — | US | claimed |
| US-11946083-B2 | Method for the microbial production of specific natural capsaicinoids | CONAGEN INC. (US) | 2024-04-02 | — | — | US | claimed |
| US-20230012268-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATION WITH STEROIDS AND A MODULATOR | BUZZELET DEVELOPMENT AND TECHNOLOGIES LTD (IL) | 2023-01-12 | — | — | US | claimed |
| US-20220403427-A1 | METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS | CONAGEN INC. (US) | 2022-12-22 | — | — | US | claimed |
| EP-4072558-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATION WITH STEROIDS AND A MODULATOR | Buzzelet Development And Technologies Ltd (IL) | 2022-10-19 | — | — | EP | claimed |
| US-20220233463-A1 | LOCAL ANESTHETIC COMPRISING A TRP CHANNEL MODULATOR | BUZZELET DEVELOPMENT AND TECHNOLOGIES LTD (IL) | 2022-07-28 | — | — | US | claimed |
| EP-4017486-A1 | COMPOSITONS FOR THE TREATMENT OF A CONDITION CHARACTERIZED BY ANANDAMIDE DEFICIENCY AND USES THEREOF | Buzzelet Development And Technologies Ltd (IL) | 2022-06-29 | — | — | EP | claimed |
| US-20220168246-A1 | COMPOSITONS FOR THE TREATMENT OF A CONDITION CHARACTERIZED BY ANANDAMIDE DEFICIENCY AND USES THEREOF | BUZZELET DEVELOPMENT AND TECHNOLOGIES LTD (IL) | 2022-06-02 | — | — | US | claimed |
| EP-3968970-A1 | LOCAL ANESTHETIC COMPRISING A TRP CHANNEL MODULATOR | Buzzelet Development And Technologies Ltd (IL) | 2022-03-23 | — | — | EP | claimed |
| EP-3946317-A1 | COMPOSITION COMPRISING CAPSAICIN OR A CAPSACINOID FOR POSTOPERATIVE PAIN CONTROL | Mestex AG (CH) | 2022-02-09 | — | — | EP | claimed |
| US-20060148903-A1 | Capsaicinoid gel formulation and uses thereof | ALGORX PHARMACEUTICALS, INC. (US) | 2006-07-06 | — | — | US | claimed |
| WO-2006058140-A2 | CAPSAICINOID GEL FORMULATION AND USES THEREOF | ALGORX PHARMACEUTICALS, INC. (US) | 2006-06-01 | — | — | WO | claimed |
| JP-2006513267-A | — | — | 2006-04-20 | — | — | JP | claimed |
| CN-1750839-A | Administration of capsaicinoids | ALGORX PHARMACEUTICALS INC (US) | 2006-03-22 | — | — | CN | claimed |
| EP-1605956-A1 | ADMINISTRATION OF CAPSAICINOIDS | Algorx Pharmaceuticals, Inc. (US) | 2005-12-21 | — | — | EP | claimed |
| US-20050020690-A1 | Infiltration of capsaicin into surgical sites and open wounds | ALGORX (US) | 2005-01-27 | — | — | US | claimed |
| US-20050019436-A1 | Injectable capsaicin | ALGORX (US) | 2005-01-27 | — | — | US | claimed |
| WO-2004058286-A1 | ADMINISTRATION OF CAPSAICINOIDS | ALGORX PHARMACEUTICALS, INC. (US) | 2004-07-15 | — | — | WO | claimed |
| EP-1135490-A1 | HUMAN VANILLOID RECEPTORS AND THEIR USES | GLAXO GROUP LIMITED (GB) | 2001-09-26 | — | — | EP | claimed |
| WO-2000032766-A1 | HUMAN VANILLOID RECEPTORS AND THEIR USES | GLAXO GROUP LIMITED (GB) | 2000-06-08 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220403427-A1 | METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS | TRPV1, CYP51A1, NAAA | CHRNB2 1306/4885CHRNB4 877/4885CHRNA3 1302/4885 |
| US-11946083-B2 | Method for the microbial production of specific natural capsaicinoids | TRPV1, CYP51A1, NAAA | CHRNB2 1306/4885CHRNB4 877/4885CHRNA3 1302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.