Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GALR2 | O43603 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 3/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2267794 | 0.78 | POLB (0.51) | POLBLMNAGALR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL6634074 | 0.78 | ALDH1A1 (0.57) | POLBLMNAGALR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL30807120 | 0.78 | ALDH1A1 (0.57) | POLBLMNAGALR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL6832051 | 0.77 | POLB (0.50) | POLBLMNAGALR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL14748024 | 0.77 | POLB (0.50) | POLBLMNAGALR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL790395 | 0.77 | POLB (0.50) | POLBLMNAGALR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL15828585 | 0.74 | LMNA (0.47) | POLBLMNAGALR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL117981 | 0.73 | FGFR4 (0.51) | POLBLMNAGALR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL30989701 | 0.73 | VCAM1 (0.47) | POLBLMNAGALR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL31315323 | 0.73 | FGFR4 (0.51) | POLBLMNAGALR2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111892579-B | Kinase inhibitors | 上海艾力斯医药科技股份有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-111875585-B | Kinase inhibitors | 上海艾力斯医药科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-111892579-A | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2020-11-06 | — | — | CN | disclosed |
| CN-111875585-A | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2020-11-03 | — | — | CN | disclosed |
| CN-106660993-B | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2020-09-11 | — | — | CN | disclosed |