Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 7/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2883985 | 0.84 | TYMS (0.36) | TYMSLMNASMN1; SMN2GRM4GRM1 | |
| SCHEMBL2884223 | 0.77 | PTGS1 (0.37) | PTGS1PTGS2TYMSLMNASMN1; SMN2 | |
| SCHEMBL2889412 | 0.76 | TP53 (0.41) | PTGS1PTGS2TYMSLMNASMN1; SMN2 | |
| SCHEMBL2883863 | 0.75 | MAPT (0.38) | TYMSLMNASMN1; SMN2GRM4GRM1 | |
| SCHEMBL2889335 | 0.74 | HTR7 (0.46) | TYMSLMNASMN1; SMN2GRM4GRM1 | |
| SCHEMBL1835277 | 0.74 | GRIA2 (0.39) | LMNASMN1; SMN2GRM4GRM1 | |
| SCHEMBL2889814 | 0.74 | LMNA (0.33) | LMNASMN1; SMN2GRM4GRM1 | |
| SCHEMBL2889576 | 0.73 | LMNA (0.33) | LMNASMN1; SMN2GRM4GRM1 | |
| SCHEMBL2887591 | 0.72 | LMNA (0.44) | PTGS1TYMSLMNASMN1; SMN2GRM4 | |
| SCHEMBL2884136 | 0.72 | LMNA (0.36) | TYMSLMNASMN1; SMN2GRM4GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130743-A1 | HETEROCYCLE-SUBSTITUTED, N-PHENYL-PHTHALAMIDE DERIVATIVES, RELATED COMPOUNDS AND THEIR USE AS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2010-05-27 | — | — | US | disclosed |
| US-7674807-B2 | Heterocycle-substituted n-phenyl-phthalamide derivatives, related compounds and their use as insecticides | BAYER CROPSCIENCE AG (DE) | 2010-03-09 | — | — | US | disclosed |
| US-20070299085-A1 | N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides | BAYER CROPSCIENCE AG (DE) | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130743-A1 | HETEROCYCLE-SUBSTITUTED, N-PHENYL-PHTHALAMIDE DERIVATIVES, RELATED COMPOUNDS AND THEIR USE AS INSECTICIDES | DDT, SQOR, CYP2S1 | PTGS1 1825/4885PTGS2 1930/4885ALOX5 1281/4885 |
| US-20070299085-A1 | N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides | CHRM1, KCNH1, DDT | PTGS1 1155/4885PTGS2 1426/4885ALOX5 3509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.