O-Xylene

O-Xylene

SCHEMBL28898303

CCOC(=O)C1C(CC)=CC(C)=CC1(CC)C(=O)OCC.Cc1ccccc1C

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.34
ALDH1A1 P00352 5/20 0.34
ADAM17 P78536 1/20 0.33
MAPT P10636 3/20 0.32
HTT P42858 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
SLC22A1 O15245 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
OPRM1 P35372 3/20 0.32
GLA P06280 1/20 0.31
OPRD1 P41143 2/20 0.31
OPRK1 P41145 2/20 0.31
SLC6A4 P31645 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28898305 0.93 GAA (0.32) TSHRGAA
SCHEMBL19585730 0.62 ADAM17 (0.57) ALDH1A1ADAM17HTTSLC22A1L3MBTL1
SCHEMBL15978559 0.62 ADAM17 (0.57) ALDH1A1ADAM17HTTSLC22A1L3MBTL1
SCHEMBL11524279 0.61 ALDH1A1 (0.39) TSHRALDH1A1MAPTHTTMEN1
O-Xylene SCHEMBL19859039 0.61 ALDH1A1 (0.62) TSHRALDH1A1MEN1KMT2ACYP1A2
O-Xylene SCHEMBL3225611 0.59 ALDH1A1 (0.64) TSHRALDH1A1HTTMEN1KMT2A
O-Xylene SCHEMBL30462319 0.59 CYP4F2 (0.54) TSHRALDH1A1MAPTKMT2AKDM4E
O-Xylene SCHEMBL27964793 0.58 ALDH1A1 (0.61) TSHRALDH1A1HTTMEN1KMT2A
O-Xylene SCHEMBL10812881 0.58 ALOX15 (0.65) TSHRALDH1A1MEN1KMT2ACYP1A2
SCHEMBL11526857 0.57 LMNA (0.33) TSHRALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111440192-B Method for preparing pinoxaden intermediate through micro-channel 山东华科化工有限公司 2022-11-25 CN claimed
CN-111440192-B Method for preparing pinoxaden intermediate through micro-channel 山东华科化工有限公司 2022-11-25 CN disclosed