Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 5/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19407345 | 0.85 | SMN1; SMN2 (0.49) | MMP8RIPK1SMN1; SMN2HIF1ASLC6A2 | |
| SCHEMBL293540 | 0.80 | MMP8 (0.51) | MMP8RIPK1SMN1; SMN2HIF1ASLC6A2 | |
| Ammonia Solution, Strong SCHEMBL9134412 | 0.79 | PTPRB (0.50) | MMP8RIPK1SMN1; SMN2HIF1ASLC6A2 | |
| Carbamic Acid SCHEMBL27809934 | 0.78 | PTPRB (0.47) | MMP8RIPK1SMN1; SMN2HIF1ASLC6A2 | |
| SCHEMBL8759 | 0.77 | SLC6A2 (0.56) | MMP8RIPK1SMN1; SMN2HIF1ASLC6A2 | |
| SCHEMBL6017676 | 0.77 | MMP8 (0.67) | MMP8RIPK1MAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3136989 | 0.76 | SLC6A2 (0.54) | MMP8RIPK1SMN1; SMN2HIF1ASLC6A2 | |
| SCHEMBL1147656 | 0.75 | SLC6A2 (0.52) | MMP8RIPK1SMN1; SMN2HIF1ASLC6A2 | |
| SCHEMBL517462 | 0.75 | SMN1; SMN2 (0.57) | MMP8RIPK1SMN1; SMN2HIF1ASLC6A2 | |
| Phentermine SCHEMBL8096007 | 0.75 | SLC6A2 (0.70) | MMP8SMN1; SMN2HIF1ASLC6A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385877-B | Dihydrofuran-2-one compound and preparation method thereof | 嘉兴学院 | 2024-02-23 | — | — | CN | claimed |
| CN-115385877-A | Dihydrofuran-2-ketone compound and preparation method thereof | 嘉兴学院 | 2022-11-25 | — | — | CN | claimed |
| CN-115385877-B | Dihydrofuran-2-one compound and preparation method thereof | 嘉兴学院 | 2024-02-23 | — | — | CN | disclosed |
| CN-115385877-A | Dihydrofuran-2-ketone compound and preparation method thereof | 嘉兴学院 | 2022-11-25 | — | — | CN | disclosed |