Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29566876 | 0.78 | ALDH1A1 (0.41) | KDM4EALDH1A1TSHR | |
| SCHEMBL5728923 | 0.76 | HTR1A (0.39) | HIF1AKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15547011 | 0.72 | HDAC8 (0.35) | KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4087934 | 0.71 | NAAA (0.40) | HIF1ATSHR | |
| SCHEMBL28820693 | 0.71 | KDM4E (0.40) | KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28048864 | 0.71 | CYP2D6 (0.47) | KDM4EALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL28271433 | 0.70 | PDE5A (0.37) | ALDH1A1 | |
| SCHEMBL4268840 | 0.70 | CYP2D6 (0.48) | SMN1; SMN2 | |
| SCHEMBL96854 | 0.70 | KCNA3 (0.62) | ALDH1A1 | |
| SCHEMBL5883528 | 0.70 | NAAA (0.43) | HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655340-A | Methods and pharmaceutical compositions for modulating autophagy | 国家医疗保健研究所 | 2020-09-11 | — | — | CN | disclosed |