Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | CYBB | P04839 | 2/20 | 0.33 |
| ▸ | NOX5 | Q96PH1 | 2/20 | 0.33 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2893237 | 0.83 | HTT (0.43) | ADRB1SMN1; SMN2KDM4EALDH1A1SLC6A2 | |
| SCHEMBL1814949 | 0.78 | ADRB1 (0.56) | ADRB1SLC6A2SLC6A4SLC6A3ALOX5 | |
| Hydrochloric Acid SCHEMBL1663296 | 0.77 | ADRB1 (0.54) | ADRB1SLC6A2SLC6A4SLC6A3ALOX5 | |
| SCHEMBL2891520 | 0.76 | P2RX7 (0.46) | — | |
| SCHEMBL2889100 | 0.72 | MEN1 (0.45) | MAPTCYBBNOX5NOX4NOX1 | |
| SCHEMBL2894048 | 0.72 | RBP4 (0.44) | — | |
| SCHEMBL2889480 | 0.72 | P2RX7 (0.42) | — | |
| SCHEMBL13664702 | 0.70 | SLC6A2 (0.58) | ADRB1ALDH1A1MAPTSLC6A2SLC6A4 | |
| SCHEMBL31176347 | 0.70 | ADRB1 (0.54) | ADRB1MAPTALOX5HTR1A | |
| SCHEMBL3653056 | 0.70 | ADRB1 (0.54) | ADRB1MAPTALOX5HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858800-B2 | Biaryl derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-12-28 | — | — | US | disclosed |
| US-20070191389-A1 | Biaryl derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1764362-A1 | BIARYL DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191389-A1 | Biaryl derivatives | GRM1, GRIN1, GRIN2B | ADRB1 56/4885SMN1; SMN2 281/4885KDM4E 4372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.